In 4 Minutes and 33 Seconds of Uniqueness, you'll win the game if you're the only one playing it for the entire duration of 273 seconds. The game checks over the internet to find out if there are other people playing it at the moment, and it will close the application if someone else starts to play it. You have to play the game for 4 minutes and 33 seconds without being interrupted to win, hence the name.
It's an exploration to what actually defines a game. You can win or fail in the game, but there is no user input or interactivity of any kind.